11+ Laughter Is The Best Medicine Quote Bible. Here are just a few references to laughter found in scripture:. It was written in the bible thousands of years ago. A merry heart doeth good like a medicine: Had a good laugh recently? Proverbs 17:22 says, "a joyful heart is good medicine, but a broken spirit dries up the bones. Even doctors will tell you that laughter is the best medicine in many situations. But a broken spirit drieth the bones. Proverbs 17:22 laughter is good medicine. That happens to come from the bible! Today's post is written by rusty wright.